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Managing Post-Op Pain at Home: Medicines
Pain after an operation (post-op pain) is common and expected. These guidelines can help you stay as comfortable as possible.
![Woman reading instructions on prescription pill bottle.](533320.img)
Taking pain medicines
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Take only the medicines that your health care provider tells you to take.
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Don't take more than prescribed. Don't take your next dose sooner than prescribed.
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Take pain medicines with some food to prevent an upset stomach.
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Don’t drink alcohol while using pain medicines.
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Don't drive while taking opioid pain medicines.
Types of pain medicines
Non-opioid
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Check with your health care provider before you take any over-the-counter (OTC) pain reliever in addition to or instead of your prescribed pain medicine.
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Non-opioids include OTC acetaminophen and ibuprofen and some prescription pain relievers.
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All relieve mild to moderate pain. Some reduce swelling.
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Possible side effects include stomach upset and bleeding. High doses may cause kidney or liver problems.
Opioid
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Opioids are available only by prescription.
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Opioids ease moderate to severe pain.
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Possible side effects include stomach upset, nausea, drowsiness, rash, and itching.
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Opioids may cause constipation. To help prevent this, eat high-fiber foods and drink plenty of water.
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Your health care provider may recommend a stool softener.
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Don't drive, make important decisions, or operate machinery while taking opioids.
When to call your doctor
Contact your health care provider or seek medical attention right away if you:
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Have nausea, vomiting, diarrhea, constipation, or stomach cramps.
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Have breathing problems or a fast, racing heart rate. (Call 911.)
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Feel tired, sluggish, or dizzy.
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Have a skin rash or other allergic symptoms.
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Have pain that is not eased with the pain medicine.
Online Medical Reviewer:
Jonas DeMuro MD
Online Medical Reviewer:
Raymond Turley Jr PA-C
Online Medical Reviewer:
Rita Sather RN
Date Last Reviewed:
2/1/2025
© 2000-2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.